Tehran University of Medical Sciences Frontiers in Biomedical Technologies 2345-5837 1 1 2014 03 30 61 67 EN Peter Knoll Department of Nuclear Medicine and PET Center, Austria S. Mirzaei Department of Nuclear Medicine and PET Center, Austria K. Schwenkenbecher Crystal Photonics GmbH, Germany T. Barthel Crystal Photonics GmbH, Germany 2015 10 13 2015 10 13 Purpose: In this work we present a handheld, solid-state detector based gamma camera system. We validated the camera physically and demonstrated the usefulness of the device for intra-operative detection of radiolabeled tissue. Methods: We measured the intrinsic uniformity, the intrinsic energy resolution, the system uniformity, the spatial resolution without scatter, the system planar uniformity, the detector shielding and the peak deviation according to the NEMA NU1-2001 standard. Results: The gamma camera can be used for isotopes with an energy range between 50-250 keV. A standard laptop is used to control of the camera and to visualize Preliminary clinical data show that the devices can be used successfully for a number of clinical applications. Conclusion: The performance evaluation of a novel handheld gamma camera shows good spatial resolution, sensitivity and energy resolution. Due to the small size and weight the portable device can be used for untraoperative acquisitions. https://fbt.tums.ac.ir/index.php/fbt/article/view/20 https://fbt.tums.ac.ir/index.php/fbt/article/download/20/19