Tehran University of Medical Sciences Frontiers in Biomedical Technologies 2345-5837 7 1 2020 03 30 14 21 Samir Derouiche Department of Cellular and Molecular Biology, Faculty of the Sciences of Nature and Life, El Oued University, El Oued 39000, El Oued, Algeria. Taissir Cheradid Department of Cellular and Molecular Biology, Faculty of the Sciences of Nature and Life, El Oued University, El Oued 39000, El Oued, Algeria Messaouda Guessoum Department of Cellular and Molecular Biology, Faculty of the Sciences of Nature and Life, El Oued University, El Oued 39000, El Oued, Algeria 2019 12 12 2020 02 14 Purpose: This study was conducted aiming at evaluating some risk factors in patients with Chronic Kidney Disease (CKD) in Djamaa (El Oued, Algeria) region. Materials and Methods: Our study is based on 77 voluntary individuals divided into healthy man and women reserved as a control with average age of 46.61± 2.84 years old and CKD patients with average age of 46.03± 2.95 years old; their origin covers the whole Djamaa (El Oued, Algeria) region and they were selected from the dialysis service of SAAD DEHLEB hospital Djamaa (El Oued Algeria). Risk of certain socio-clinical factors has been estimated by the determination of the value of Odd Ratio (OR). Results: Our study reports show a strong association between clinical factors such as Diabetes, urinary problems and Arterial hyper pressure (OR= 5.135, 6.60 and 78.276; P ≤0.05) with chronic kidney disease, respectively, but in this study we show that the Renal herbal medicine and History of kidney disease are the most dangerous risk factors, (OR = 20.00, OR =25,45 ; p≤0.001), respectively, for spices and Amount of water (OR ranging from 0.232 to 0.352; P ≤0.032) are important protective factors against this disease. Conclusion: Lifestyle is a contributing factor in CKD attainment in the region of Djamaa (El Oued, Algeria), which requires high sensitivity to modify these behaviors for limited progression of the disease in this region. https://fbt.tums.ac.ir/index.php/fbt/article/view/243 https://fbt.tums.ac.ir/index.php/fbt/article/download/243/150