Tehran University of Medical Sciences Frontiers in Biomedical Technologies 2345-5837 11 1 2024 01 01 31 40 Sanaz Khomami Department of Psychology, Faculty of Education and Psycology Alzahra University, Tehran, Iran Roshanak Khodabakhsh Pirkalani Department of Psychology, Faculty of Education and Psycology Alzahra University, Tehran, Iran 2022 09 08 2022 11 13 Purpose: Obsessive-Compulsive Disorder (OCD) is a mental and behavioral disorder in which an individual has intrusive thoughts and rituals which decrease the distress. It seems that there are many treatments such as EX/RP, repetitive Transcranial Magnetic Stimulation (rTMS), medications or mindfulness for OCD, but there is no single effective treatment yet. In this study, we investigated a multi-element daily program on symptom reduction of OCD people. Materials and Methods: In a quasi-experimental design 13 patients were included in the study and received daily rTMS with EX/RP and biofeedback. We utilized BDI, BAI, and YBOCS tools to collect data before and after the treatment and in the subsequent one-month follow-up. Results: According to the BDI, BAI, and YBOCS results, the decrease in score was observed at the p<0.001 level and the changes were significant after a one-month follow-up period. Conclusion: The results indicated that the combination of sequenced treatments simultaneously such as rTMS and biofeedback with exposure therapy can facilitate the engagement and enhancement of self-control and distress tolerance. https://fbt.tums.ac.ir/index.php/fbt/article/view/540 https://fbt.tums.ac.ir/index.php/fbt/article/download/540/381