Tehran University of Medical Sciences Frontiers in Biomedical Technologies 2345-5837 0 0 2025 01 11 989 989 EN Khadija Masood The University of Lahore S Muhammad Yousaf Farooq The University of Lahore Hamnah Fatima University Institute of radiological sciences and medical imaging technology, faculty of Allied health sciences, The University of Lahore. Syeda Masooma Raza Naqvi University Institute of radiological sciences and medical imaging technology, faculty of Allied health sciences, The University of Lahore. Mahrukh Amna University Institute of radiological sciences and medical imaging technology, faculty of Allied health sciences, The University of Lahore. Amna khushi University Institute of radiological sciences and medical imaging technology, faculty of Allied health sciences, The University of Lahore. Rubiqa Muhammad Riaz University Institute of radiological sciences and medical imaging technology, faculty of Allied health sciences, The University of Lahore. Rana Saqib Javed University Institute of radiological sciences and medical imaging technology, faculty of Allied health sciences, The University of Lahore. 2024 04 04 2024 12 30 Background: Patients with diabetes are more likely to develop polyhydramnios. The rate of Polyhydramnios among diabetic patients is ascending when contrasted with non-diabetic patients. Objective: To compare the amniotic fluid index of diabetics and non-diabetics using sonography. Methods: 200 people participated in a case-control study, 100 of whom were diabetic and the other 100 were non-diabetic. Toshiba XARIO XG was used in the study at the university ultrasound clinic in Green Town. It has a convex probe of 3.5-7.5 MHz frequency. All patients with diabetes and gestational diabetes of age 18-45 years are included during 2nd & 3rd trimesters. Any underlying pathologies like hypertension, multiple gestations were excluded in this study. SPSS version 25.0 was utilized for the analysis of the data.  Results: The mean amniotic fluid index in diabetics and non-diabetics was 21.19 and 13.20 respectively.  In both diabetics and non-diabetics, the amniotic fluid index was found to be statistically significant (p=0.000). The chi-square analysis shows a significant association between AFI category and diabetes status. With the Diabetic group having a higher proportion of cases with Polyhydramnios AFI category and a lower proportion of cases with Normal AFI category compared to the Non-diabetic group. The mean estimated fetal weight in diabetics and non-diabetics was 1341.64 and 1372.53 respectively. Result shows that there was no significant difference in the estimated weight of the fetus between diabetic and non-diabetic females (p=0.088). Conclusions: Study concluded that diabetes during pregnancy is associated with a significant increase in amniotic fluid levels, leading to a higher likelihood of polyhydramnios. https://fbt.tums.ac.ir/index.php/fbt/article/view/989 https://fbt.tums.ac.ir/index.php/fbt/article/download/989/476