Establishing Pediatric Thoracic Diagnostic Reference Levels Using CALDOSE_X: A Data-Driven Approach to Optimizing Radiation Safety
Abstract
Objective: In Morocco, significant disparities exist in observing national radiation protection standards, particularly in conventional radiology for pediatric patients. This cross-sectional study aims to establish Moroccan diagnostic reference levels (DRLs) for pediatric thorax radiography.
Methods: Thorax radiography examinations of 208 pediatric patients (newborns up to 18 years old) from four public hospitals in Morocco were evaluated. Patient demographics (age, gender, weight), and scan parameters were recorded to calculate radiation doses using CALDOSE_X 5.0 software, quantifying entrance surface air kerma (ESAK) in mGy. The study samples were divided into five age groups (age <1 month, 1 month ≤ age< 4 years, 4 years ≤ age< 10 years, 10 years ≤ age< 14 years, and 14 years ≤ age < 18 years). The third quartile (P75) of calculated ESAK in mGy and kinetic energy released per unit mass (KERMA)-area product (KAP), in mGy.cm² for each group were analyzed. Statistical analysis was performed using SPSS version 21.
Results: The P75 values for ESAK (mGy) and KAP (mGy.cm²) diagnostic reference levels across age groups were: 0.61, 0.69, 0.68, 0.82, and 1.29 for ESAK, and 350.25, 566.07, 499.14, 950.62, and 1816.06 for KAP. The calculated regional DRLs for pediatric thorax radiography exceeded the published values for thorax protocols in some European countries. The irradiated surfaces significantly impacted the received doses of patients up to 10 years old (p-values of 0.004, 0.000, and 0.001).
Conclusions: Adapting the irradiation surface to patient morphology is crucial, requiring precise control over exposure factors, radiation field size, and protocol selection.
2- H. Nahangi and A. Chaparian, "Assessment of radiation risk to pediatric patients undergoing conventional X-ray examinations." Radioprotection, Vol. 50 (No. 1), pp. 19-25, (2015).
3- Karen M. Wieseler, Puneet Bhargava, Kalpana M. Kanal, Sandeep Vaidya, Brent K. Stewart, and Manjiri K. Dighe, "Imaging in Pregnant Patients: Examination Appropriateness." RadioGraphics, Vol. 30 (No. 5), pp. 1215-29, (2010).
4- A. Chaparian and M. Aghabagheri, "Fetal radiation doses and subsequent risks from X-ray examinations: Should we be concerned?" Iran J Reprod Med, Vol. 11 (No. 11), pp. 899-904, Nov (2013).
5- J. Valentin, "Biological effects after prenatal irradiation (embryo and fetus)." Annals of the ICRP, Vol. 33 (No. 1-2), pp. 1-206, (2003).
6- R. Kumar and O. De Jesus, "Radiation Effects On The Fetus." in StatPearls. Treasure Island (FL), (2024).
7- Mohammed Khalil Saeed, Yousif Abdallah, Ibrahim Y. Hakeem, and Fawaz F. Alqahtani, "Patient radiation dose estimation during pelvis, hip joint and lumber spine radiography in Majmaah city, Saudi Arabia hospital." Radiation Physics and Chemistry, Vol. 209p. 110990, (2023).
8- Emily Ashworth, Liam Woods, and J. Valmai Cook, "Diagnostic reference levels in paediatric fluoroscopy: how does a secondary referral centre compare with 2018 European guidelines?" The British Journal of Radiology, Vol. 94 (No. 1123), p. 20201269, (2021).
9- Martin Uffmann and Cornelia Schaefer-Prokop, "Digital radiography: The balance between image quality and required radiation dose." European Journal of Radiology, Vol. 72 (No. 2), pp. 202-08, (2009).
10- D. N. DeMaio et al., "Best Practices in Digital Radiography." Radiol Technol, Vol. 91 (No. 2), pp. 198-201, Nov (2019).
11- C. Martin, "The importance of radiation quality for optimisation in radiology." Biomed Imaging Interv J, Vol. 3 (No. 2), p. e38, Apr (2007).
12- W. Elshami, M. M. Abuzaid, M. M. Gibril, A. Sulieman, and D. A. Bradley, "Impact of high kilo-voltage peak technique on radiation dose for neonates undergoing chest radiography: Experimental study." Radiation Physics and Chemistry, Vol. 199p. 110327, (2022).
13- INTERNATIONAL ATOMIC ENERGY AGENCY, Dosimetry in Diagnostic Radiology for Paediatric Patients. Vienna: IAEA Human Health Series (2014).
14- E. Vañó et al., "ICRP Publication 135: Diagnostic Reference Levels in Medical Imaging." Annals of the ICRP, Vol. 46 (No. 1), pp. 1-144, (2017).
15- P. Roch, D. Célier, C. Dessaud, and C. Etard, "Les niveaux de référence diagnostiques en France : une perception contrastée face à un dispositif perfectible mais efficace." Radioprotection, Vol. 53 (No. 1), pp. 13-19, (2018).
16- Yasuki Asada and Takuma Ichikawa, "Consideration of diagnostic reference levels for pediatric chest X-ray examinations." Radiological Physics and Technology, Vol. 12 (No. 4), pp. 382-87, (2019).
17- Jochen Billinger, Robert Nowotny, and Peter Homolka, "Diagnostic reference levels in pediatric radiology in Austria." European Radiology, Vol. 20 (No. 7), pp. 1572-79, (2010).
18- Barry F. Wall, "Diagnostic reference levels in the X–ray department." European Radiology Supplements, Vol. 14 (No. S1), pp. 66-73, (2004).
19- T. Kiljunen, H. Järvinen, and S. Savolainen, "Diagnostic reference levels for thorax X-ray examinations of paediatric patients." The British Journal of Radiology, Vol. 80 (No. 954), pp. 452-59, (2007).
20- European Commission and Directorate-General for Energy, European guidelines on diagnostic reference levels for paediatric imaging. Publications Office, (2018).
21- I. G. Shatskiy, A. Yu. Gryaznov, and Yu. N. Potrakhov, "Assessment of models of diagnostic reference levels for children on radiography." AIP Conference Proceedings, Vol. 2726 (No. 1), p. 020022, (2023).
22- A. Almen, J. Guethjonsdottir, N. Heimland, B. Hojgaard, H. Waltenburg, and A. Widmark, "Paediatric diagnostic reference levels for common radiological examinations using the European guidelines." Br J Radiol, Vol. 95 (No. 1130), p. 20210700, Feb 1 (2022).
23- R. Kramer, H. J. Khoury, and J. W. Vieira, "CALDose_X—a software tool for the assessment of organ and tissue absorbed doses, effective dose and cancer risks in diagnostic radiology." Physics in Medicine and Biology, Vol. 53 (No. 22), pp. 6437-59, (2008).
24- M. K. Saeed and Y. Almalki, "Assessment of the radiation dose associated with X-ray examinations using the DoseCal and CALDose_X software packages." International Journal of Radiation Research, Vol. 20 (No. 1), pp. 191-97, (2022).
25- ICRP, "Preface, Executive Summary and Glossary." Annals of the ICRP, Vol. 37 (No. 2-4), pp. 9-34, (2007).
26- G. Paulo, E. Vaño, and A. Rodrigues, "Diagnostic reference levels in plain radiography for paediatric imaging: A Portuguese study." Radiography, Vol. 22 (No. 1), pp. e34-e39, (2016).
27- Libby Brateman, "The AAPM/RSNA Physics Tutorial for Residents." RadioGraphics, Vol. 19 (No. 4), pp. 1037-55, (1999).
28- Suhaib Alameen, Fatima A. A. Badrey, Abdulrahman S. Abdullateef, and Abdelfatah M. Ahmed, "Assessment of ESAK and ED for Adult’s Patients Examined by Computed Radiography." International Journal of Medical Physics, Clinical Engineering and Radiation Oncology, Vol. 05 (No. 04), pp. 281-87, (2016).
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