Thyroid Cancer Risk in Patients Undergoing 64 Slice Brain and Paranasal Sinuses Computed Tomography
Abstract
Purpose: Computed Tomography (CT) is a fundamental part of diagnosis of diseases. During CT examinations organs in and out of scanned volume are exposed to ionization radiation. The aim of this study was Estimation Thyroid cancer risk in Patients who Underwent 64 Slice brain and paranasal sinuses CT scan.
Materials and Methods: With permission from the authors and editor, data related to thyroid dose of 40 patients in Mazyar et al.'s paper was used and by using Biological Effects of Ionizing Radiation (BEIR)VII model thyroid cancer risk was calculated for different ages at exposure in male and female.
Results: In both brain and paranasal sinuses CT, ERR values in female patients were twice as many as those in male patients. At age range from 20 to 40 years, ERR was considerably more than at age range 40-60 years since young patients are more radiosensitive than old patients.
Conclusion: The calculations of ERR indicate that PNS and brain CT increase the theoretical risk of thyroid cancer incidence. Although the ERR values are low, impacts on the thyroid cancer incidence should not be disregarded.
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2- D. Hart and B. Wall, "UK population dose from medical X-ray examinations," European journal of radiology, vol. 50, no. 3, pp. 285-291, 2004.
3- E. Seeram, Computed Tomography-E-Book: Physical Principles, Clinical Applications, and Quality Control. Elsevier Health Sciences, 2015.
4- F. A. Mettler Jr, P. W. Wiest, J. A. Locken, and C. A. Kelsey, "CT scanning: patterns of use and dose," Journal of radiological Protection, vol. 20, no. 4, p. 353, 2000.
5- S. J. Schonfeld, C. Lee, and A. B. de Gonzalez, "Medical exposure to radiation and thyroid cancer," Clinical Oncology, vol. 23, no. 4, pp. 244-250, 2011.
6- G. Pellegriti, F. Frasca, C. Regalbuto, S. Squatrito, and R. Vigneri, "Worldwide increasing incidence of thyroid cancer: update on epidemiology and risk factors," Journal of cancer epidemiology, vol. 2013, 2013.
7- S. R. Baker and W. A. Bhatti, "The thyroid cancer epidemic: is it the dark side of the CT revolution?," European journal of radiology, vol. 60, no. 1, pp. 67-69, 2006.
8- H. Wallace, C. Martin, D. Sutton, D. Peet, and J. Williams, "Establishment of scatter factors for use in shielding calculations and risk assessment for computed tomography facilities," Journal of Radiological Protection, vol. 32, no. 1, p. 39, 2012.
9- C. Moreno, E. Cenizo, C. Bodineau, B. Mateo, and E. Ortega, "Analysis of shielding calculation methods for 16-and 64-slice computed tomography facilities," Journal of Radiological Protection, vol. 30, no. 3, p. 557, 2010.
10- J. Cole and D. Platten, "A comparison of shielding calculation methods for multi-slice computed tomography (CT) systems," Journal of Radiological Protection, vol. 28, no. 4, p. 511, 2008.
11- A. Maziar, R. Paydar, G. Azadbakht, and D. Shahbazi-Gahrouei, "Estimation of absorbed dose of the thyroid gland in patients undergoing 64-slice head computed tomography and comparison the results with ImPACT software and computed tomography scan dose index," Journal of medical signals and sensors, vol. 9, no. 3, p. 190, 2019.
12- D. J. Pawel and J. S. Puskin, "US Environmental Protection Agency radiogenic risk models and projections for the US population," Health Physics, vol. 102, no. 6, pp. 646-656, 2012.
13- N. Narendran, L. Luzhna, and O. Kovalchuk, "Sex difference of radiation response in occupational and accidental exposure," Frontiers in genetics, vol. 10, 2019.
14- J. D. Mathews et al., "Cancer risk in 680 000 people exposed to computed tomography scans in childhood or adolescence: data linkage study of 11 million Australians," Bmj, vol. 346, p. f2360, 2013.
15- M. Mazonakis, A. Tzedakis, J. Damilakis, and N. Gourtsoyiannis, "Thyroid dose from common head and neck CT examinations in children: is there an excess risk for thyroid cancer induction?," European radiology, vol. 17, no. 5, pp. 1352-1357, 2007.
16- B. Huang, J. Li, M. W. Law, J. Zhang, Y. Shen, and P. Khong, "Radiation dose and cancer risk in retrospectively and prospectively ECG-gated coronary angiography using 64-slice multidetector CT," The British journal of radiology, vol. 83, no. 986, pp. 152-158, 2010.
17- S. C. Bushong, Radiologic science for technologists-E-book: physics, biology, and protection. Elsevier Health Sciences, 2013.
18- T. A. Jaffe, J. K. Hoang, T. T. Yoshizumi, G. Toncheva, C. Lowry, and C. Ravin, "Radiation dose for routine clinical adult brain CT: variability on different scanners at one institution," American Journal of Roentgenology, vol. 195, no. 2, pp. 433-438, 2010.
19- M. T. Bahreyni Toossi et al., "Assessment of Radiation Dose to the Lens of the Eye and Thyroid of Patients Undergoing Head and Neck Computed Tomography at Five Hospitals in Mashhad, Iran," Iranian Journal of Medical Physics, vol. 15, no. 4, pp. 226-230, 2018.
| Files | ||
| Issue | Vol 7 No 2 (2020) | |
| Section | Original Article(s) | |
| DOI | https://doi.org/10.18502/fbt.v7i2.3855 | |
| Keywords | ||
| Thyroid Cancer Risk Biological Effects of Ionizing Radiation VII Model Computed Tomography Brain Computed Tomography Paranasal Sinuses Computed Tomography | ||
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This work is licensed under a Creative Commons Attribution-NonCommercial 4.0 International License. |
How to Cite
1.
Ghaznavi H. Thyroid Cancer Risk in Patients Undergoing 64 Slice Brain and Paranasal Sinuses Computed Tomography. Frontiers Biomed Technol. 2020;7(2):100-104.
