Common and Uncommon Imaging Appearances of COVID-19 Pneumonia in Young and Middle-Aged Group and Elderly Group

Alireza Mahmoudabadi; Hamed Masoumi; Mohammad Keshtkar; Arash Azhideh; Hamidreza Haghighatkhah

doi:10.18502/fbt.v8i2.6516

Common and Uncommon Imaging Appearances of COVID-19 Pneumonia in Young and Middle-Aged Group and Elderly Group

Hamidreza Haghighatkhah

Abstract

Purpose: In this study, we retrospectively evaluated chest Computed Tomography (CT) imaging manifestations of the patients with Coronavirus Disease 2019 (COVID-19) to simplify prompt early diagnosis of disease and speed up needed actions for infected patients.

Materials and Methods: Totally, 75 patients who laboratory confirmed COVID-19 pneumonia were enrolled in this study. CT images, demographic and some clinical data of all patients were collected and analyzed retrospectively. Furthermore, for comparison, the patients were divided into two groups as follows: the young and middle-aged group (< 60 years old) and the elderly group (≥ 60 years old).

Results: Based on the evaluation of CT images, 33 patients (44%) showed Ground-Glass Opacity (GGO), 15 patients (20%) showed consolidation, 24 patients (32%) showed mixed GGO and consolidation, 2 patients (2.6%) had bronchial wall thickening, 10 patients (13.3%) had a crazy paving sign, 35 patients (46.6%) had air bronchogram and, 7 patients (9.3%) had cavitation and 2 patients (2.6%) had a tree in the bud. CT images of 3 patients (4%) were normal. In terms of out of lung changes, lymphadenopathy was observed in one patient (1.3%), pleural effusion in 12 patients (16%), and pericardial effusion in 2 patients (2.6%). Lesions were found predominantly in the peripheral (57.3%) and the lower lung region (60%).

Conclusion: CT images of the COVID-19 patients showed various aspects, mainly GGO, consolidation, mixed GGO and consolidation, and air bronchogram. Lesion distribution was predominantly in lower lung region, bilateral and peripheral. Pleural effusion and multiple lobe involvement were significantly higher in the elderly group than that of the young and middle-aged group.

1- C. Huang et al., "Clinical features of patients infected with 2019 novel coronavirus in Wuhan, China," The Lancet, vol. 395, no. 10223, pp. 497-506, 2020.
2- N. Zhu et al., "A novel coronavirus from patients with pneumonia in China, 2019," New England Journal of Medicine, 2020.
3- Q. Li et al., "Early transmission dynamics in Wuhan, China, of novel coronavirus–infected pneumonia," New England Journal of Medicine, 2020.
4- M. Roser, H. Ritchie, and E. Ortiz-Ospina, "Coronavirus Disease (COVID-19)–Statistics and Research," Our World in Data, 2020.
5- A. R. Fehr and S. Perlman, "Coronaviruses: an overview of their replication and pathogenesis," in Coronaviruses: Springer, pp. 1-23, 2015.
6- A. Filatov, P. Sharma, F. Hindi, and P. S. Espinosa, "Neurological complications of coronavirus disease (covid-19): encephalopathy," Cureus, vol. 12, no. 3, p. e7352, 2020.
7- Y. C. Li, W. Z. Bai, and T. Hashikawa, "The neuroinvasive potential of SARS‐CoV2 may play a role in the respiratory failure of COVID‐19 patients," Journal of medical virology, 2020.
8- R. L. Graham, E. F. Donaldson, and R. S. Baric, "A decade after SARS: strategies for controlling emerging coronaviruses," Nature Reviews Microbiology, vol. 11, no. 12, pp. 836-848, 2013.
9- W. H. Organization, "Novel coronavirus (2019-nCoV)," Situation report, vol. 28, 2020.
10- W. Wang, J. Tang, and F. Wei, "Updated understanding of the outbreak of 2019 novel coronavirus (2019‐nCoV) in Wuhan, China," Journal of medical virology, vol. 92, no. 4, pp. 441-447, 2020.
11- G. O. o. N. H. Committee, "Notice on the issuance of a program for the diagnosis and treatment of novel coronavirus (2019-nCoV) infected pneumonia (trial revised fifth edition)," ed, 2020.
12- Y. Yang et al., "Laboratory diagnosis and monitoring the viral shedding of 2019-nCoV infections," medRxiv, 2020.
13- M. Chung et al., "CT imaging features of 2019 novel coronavirus (2019-nCoV)," Radiology, p. 200230, 2020.
14- S. Kooraki, M. Hosseiny, L. Myers, and A. Gholamrezanezhad, "Coronavirus (COVID-19) outbreak: what the department of radiology should know," Journal of the American college of radiology, 2020.
15- A. Mahdavi et al., "Radiologic Management of COVID-19: Preliminary Experience of the Iranian Society of Radiology COVID-19 Consultant Group (ISRCC)," Iranian Journal of Radiology, no. In Press, 2020.
16- H. Xu et al., "Analysis and Prediction of False Negative Results for SARS-CoV-2 Detection with Pharyngeal Swab Specimen in COVID-19 Patients: A Retrospective Study," MedRxiv, 2020.
17- A. Bernheim et al., "Chest CT findings in coronavirus disease-19 (COVID-19): Relationship to duration of infection," Radiology, p. 200463, 2020.
18- T. Ai et al., "Correlation of chest CT and RT-PCR testing in coronavirus disease 2019 (COVID-19) in China: a report of 1014 cases," Radiology, p. 200642, 2020.
19- H. Shi et al., "Radiological findings from 81 patients with COVID-19 pneumonia in Wuhan, China: a descriptive study," The Lancet Infectious Diseases, 2020.
20- W. Zhao, Z. Zhong, X. Xie, Q. Yu, and J. Liu, "Relation between chest CT findings and clinical conditions of coronavirus disease (COVID-19) pneumonia: a multicenter study," American Journal of Roentgenology, vol. 214, no. 5, pp. 1072-1077, 2020.
21- W. Yang et al., "Clinical characteristics and imaging manifestations of the 2019 novel coronavirus disease (COVID-19): A multi-center study in Wenzhou city, Zhejiang, China," Journal of Infection, 2020.
22- R. Nijman, M. Thompson, M. van Veen, R. Perera, H. Moll, and R. Oostenbrink, "Derivation and validation of age and temperature specific reference values and centile charts to predict lower respiratory tract infection in children with fever: prospective observational study," Bmj, vol. 345, 2012.
23- S. Zhou, Y. Wang, T. Zhu, and L. Xia, "CT features of coronavirus disease 2019 (COVID-19) pneumonia in 62 patients in Wuhan, China," American Journal of Roentgenology, vol. 214, no. 6, pp. 1287-1294, 2020.
24- X. He, J. Zheng, J. Ren, G. Zheng, and L. Liu, "Chest high-resolution computed tomography imaging findings of coronavirus disease 2019 (Covid-19) pneumonia," International Journal of Radiation Research, vol. 18, no. 2, pp. 343-349, 2020.
25- P. Zhou et al., "A pneumonia outbreak associated with a new coronavirus of probable bat origin," nature, vol. 579, no. 7798, pp. 270-273, 2020.
26- D. Caruso et al., "Chest CT features of COVID-19 in Rome, Italy," Radiology, p. 201237, 2020.
27- H. Lu, H. Rui, Y. Pengxin, W. Shaokang, and X. Liming, "A correlation study of CT and clinical features of different clinical types of 2019 novel coronavirus pneumonia," Chin J Radiol, vol. 54, pp. E003-E003, 2020.
28- J. Cao, J. Zhou, Q. Long, G. Ling, and X. Liao, "Clinical and Imaging Features of Novel Coronavirus Pneumonia in the Elderly Compared with Young and Middle-Aged Individuals," Iranian Journal of Radiology, vol. 17, no. 4, 2020.

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Issue	Vol 8 No 2 (2021)
Section	Original Article(s)
DOI	https://doi.org/10.18502/fbt.v8i2.6516
Keywords
Chest Computed Tomography Coronavirus Disease 2019 Imaging Manifestation

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Mahmoudabadi A, Masoumi H, Keshtkar M, Azhideh A, Haghighatkhah H. Common and Uncommon Imaging Appearances of COVID-19 Pneumonia in Young and Middle-Aged Group and Elderly Group. Frontiers Biomed Technol. 2021;8(2):123-130.

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