Assessment of Physical and Mechanical Parameters of the Left Ventricle by Speckle Tracking Technique for Prediction Coronary Artery Disease Patients
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Abstract
Purpose: The goal of the study was to identify earlier pathology of the Left Ventricle (LV) using Speckle Tracking Echocardiography (STE) without angiography results for detecting Coronary Artery Disease (CAD) patients who have need invasive coronary reperfusion.
Materials and Methods: A total of seventy-five referral patients to angiography (mean age 57±9 years) with chest pain, underwent Two-Dimensional Echocardiography (2D-ECG). Conventional echocardiographic parameters were calculated for the assessment of LV function. End systole and early diastole longitudinal strain, strain rate, and velocity with 2D-STE were estimated to evaluate myocardial function. Discriminated analysis was performed to detect CAD patients from the healthy group.
Results: According to the angiography results, patients were divided into CAD group (n=55) and healthy group (n=20). There was a significant decrease in longitudinal strain, strain rate, and velocity in patients with CAD compared to the healthy group (systolic longitudinal strain for CAD group -15.9±2.2% vs. -19.6±2.2% for healthy group and early diastolic longitudinal strain for CAD patients -9.5±1.2% vs. -12.0±1.3% for the healthy group) (P-value<0.05). Discriminate analysis of end-systolic and early diastolic longitudinal strain with 81.8% and 89.1% indicated the highest sensitivity, respectively.
Conclusions: End systolic and early diastolic longitudinal strain parameters derived with the STE method are superior predictors for detecting CAD patients referred to angiography for revascularization.
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19- Hassan Moladoust, Manijhe Mokhtari‐Dizaji, and Zahra Ojaghi‐Haghighi, "Evaluation of left anterior descending coronary artery stenosis severity from myocardial end‐diastolic wall stress estimated by tissue‐Doppler imaging." Journal of Clinical Ultrasound, Vol. 41 (No. 5), pp. 297-304, (2013).
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21- Kaoru Dohi, Emiyo Sugiura, and Masaaki Ito, "Utility of strain-echocardiography in current clinical practice." Journal of echocardiography, Vol. 14 (No. 2), pp. 61-70, (2016).
2- Lin Li, Ping-Yang Zhang, Hong Ran, Jing Dong, Ling-Ling Fang, and Qian-Shan Ding, "Evaluation of left ventricular myocardial mechanics by three-dimensional speckle tracking echocardiography in the patients with different graded coronary artery stenosis." The international journal of cardiovascular imaging, Vol. 33 (No. 10), pp. 1513-20, (2017).
3- Matteo Cameli et al., "Echocardiographic assessment of left ventricular systolic function: from ejection fraction to torsion." Heart failure reviews, Vol. 21 (No. 1), pp. 77-94, (2016).
4- Brage H Amundsen et al., "Noninvasive myocardial strain measurement by speckle tracking echocardiography: validation against sonomicrometry and tagged magnetic resonance imaging." Journal of the American College of Cardiology, Vol. 47 (No. 4), pp. 789-93, (2006).
5- Sebastian I Sarvari et al., "Layer-specific quantification of myocardial deformation by strain echocardiography may reveal significant CAD in patients with non–ST-segment elevation acute coronary syndrome." JACC: Cardiovascular Imaging, Vol. 6 (No. 5), pp. 535-44, (2013).
6- Aleksandra Żebrowska et al., "Left ventricular systolic function assessed by speckle tracking echocardiography in athletes with and without left ventricle hypertrophy." Journal of clinical medicine, Vol. 8 (No. 5), p. 687, (2019).
7- Murathan Kucuk, Can Ramazan Oncel, Aytul Belgi Yıldırım, Fatih Canan, and Mehmet Murat Kuloglu, "Evaluation of subclinical left ventricular systolic dysfunction in chronic asymptomatic alcoholics by speckle tracking echocardiography." BioMed Research International, Vol. 2017(2017).
8- Manish Bansal and Ravi R Kasliwal, "How do I do it? Speckle-tracking echocardiography." Indian heart journal, Vol. 65 (No. 1), p. 117, (2013).
9- Lars Gunnar Klaeboe and Thor Edvardsen, "Echocardiographic assessment of left ventricular systolic function." Journal of echocardiography, Vol. 17 (No. 1), pp. 10-16, (2019).
10- In‐Chang Hwang et al., "Comparison of mid‐to long‐term clinical outcomes between anatomical testing and usual care in patients with suspected coronary artery disease: A meta‐analysis of randomized trials." Clinical cardiology, Vol. 40 (No. 11), pp. 1129-38, (2017).
11- Idan Roifman, Harindra C Wijeysundera, Peter C Austin, Mohammad R Rezai, Graham A Wright, and Jack V Tu, "Comparison of anatomic and clinical outcomes in patients undergoing alternative initial noninvasive testing strategies for the diagnosis of stable coronary artery disease." Journal of the American Heart Association, Vol. 6 (No. 7), p. e005462, (2017).
12- Mustafa Adem Yılmaztepe and Fatih Mehmet Uçar, "Layer-specific strain analysis in patients with suspected stable angina pectoris and apparently normal left ventricular wall motion." Cardiovascular ultrasound, Vol. 16 (No. 1), pp. 1-9, (2018).
13- Patrick Collier, Dermot Phelan, and Allan Klein, "A test in context: myocardial strain measured by speckle-tracking echocardiography." Journal of the American College of Cardiology, Vol. 69 (No. 8), pp. 1043-56, (2017).
14- Sherif F Nagueh et al., "Recommendations for the evaluation of left ventricular diastolic function by echocardiography: an update from the American Society of Echocardiography and the European Association of Cardiovascular Imaging." European Journal of Echocardiography, Vol. 17 (No. 12), pp. 1321-60, (2016).
15- Thibault Caspar et al., "Longitudinal 2D strain can help diagnose coronary artery disease in patients with suspected non-ST-elevation acute coronary syndrome but apparent normal global and segmental systolic function." International journal of cardiology, Vol. 236pp. 91-94, (2017).
16- Egle Rumbinaite et al., "Early and late diastolic strain rate vs global longitudinal strain at rest and during dobutamine stress for the assessment of significant coronary artery stenosis in patients with a moderate and high probability of coronary artery disease." Echocardiography, Vol. 33 (No. 10), pp. 1512-22, (2016).
17- Hanan Radwan and Ekhlas Hussein, "Value of global longitudinal strain by two dimensional speckle tracking echocardiography in predicting coronary artery disease severity." The Egyptian Heart Journal, Vol. 69 (No. 2), pp. 95-101, (2017).
18- Sara Shimoni et al., "Differential effects of coronary artery stenosis on myocardial function: the value of myocardial strain analysis for the detection of coronary artery disease." Journal of the American Society of Echocardiography, Vol. 24 (No. 7), pp. 748-57, (2011).
19- Hassan Moladoust, Manijhe Mokhtari‐Dizaji, and Zahra Ojaghi‐Haghighi, "Evaluation of left anterior descending coronary artery stenosis severity from myocardial end‐diastolic wall stress estimated by tissue‐Doppler imaging." Journal of Clinical Ultrasound, Vol. 41 (No. 5), pp. 297-304, (2013).
20- Chong Liu et al., "Multilayer longitudinal strain at rest may help to predict significant stenosis of the left anterior descending coronary artery in patients with suspected non-ST-elevation acute coronary syndrome." The international journal of cardiovascular imaging, Vol. 32 (No. 12), pp. 1675-85, (2016).
21- Kaoru Dohi, Emiyo Sugiura, and Masaaki Ito, "Utility of strain-echocardiography in current clinical practice." Journal of echocardiography, Vol. 14 (No. 2), pp. 61-70, (2016).
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| Issue | Vol 9 No 3 (2022) | |
| Section | Original Article(s) | |
| DOI | https://doi.org/10.18502/fbt.v9i3.9647 | |
| Keywords | ||
| Strain Strain Rate Speckle Tracking Echocardiography | ||
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How to Cite
1.
Ahmadi ZA, Mokhtari Dizaji M, Sadeghpour A, Khesali H, Firouzi A. Assessment of Physical and Mechanical Parameters of the Left Ventricle by Speckle Tracking Technique for Prediction Coronary Artery Disease Patients. Frontiers Biomed Technol. 2022;9(3):206-213.
