Comparison of Hematological Parameters between Diagnostic Radiation Workers and Non-Radiation Workers
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Abstract
Purpose: Radiation workers are exposed to chronic effects due to long-term exposure to low levels of ionizing radiation. One of the biological indicators to evaluate these chronic radiation effects is the study of the hematopoietic system. The purpose of this study is to compare the changes in blood parameters of radiology staff and staff of other wards of the hospital.
Materials and Methods: In this study, 47 radiology staff working in the radiology department of the hospital as the study group and 98 personnel in other departments as the control group were included. Demographic data including age, gender, and work experience were obtained. Hematological parameters were extracted from the complete blood count tests of participants.
Results: The results of this study showed that the MCH and MCHC parameters significantly decreased in the male study group, whereas no significant differences were observed in the blood parameters of the female study group in comparison to those of the control group. There was a significant positive correlation between the parameters of Hemoglobin and age. There was a significant negative correlation between work experience and white blood cells, while there was a significant positive correlation between work experience and Hemoglobin.
Conclusion: Correlation between collective absorbed dose and changes in blood parameters is suggested for future studies. Based on the results of this study and other studies, it can be concluded that long-term exposure to low levels of radiation may change blood parameters. Therefore, regular and periodic complete blood count tests along with absorbed dose monitoring of radiation workers are recommended.
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5- Anju Shrivastava, Lalit Mohan Aggarwal, Surendra Pratap Mishra, Hari Dev Khanna, Uday Pratap Shahi, and Satyajit Pradhan, "Free radicals and antioxidants in normal versus cancerous cells—An overview." Indian Journal of Biochemistry and Biophysics (IJBB), Vol. 56 (No. 1), pp. 7-19, (2019).
6- Qin-Qi Wang et al., "Ionizing Radiation-Induced Brain Cell Aging and the Potential Underlying Molecular Mechanisms." Cells, Vol. 10 (No. 12), p. 3570, (2021).
7- Flávio Manoel Rodrigues da Silva-Júnior, Ronan Adler Tavella, Caroline Lopes Feijo Fernandes, Alexandra Silveira Mortola, Gianni Goulart Peraza, and Edariane Menestrino Garcia, "Genotoxic risk in health-care professionals occupationally exposed to low doses of ionizing radiation." Toxicology and Industrial Health, Vol. 36 (No. 5), pp. 356-70, (2020).
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9- Natalia Saltybaeva, Katharina Martini, Thomas Frauenfelder, and Hatem Alkadhi, "Organ dose and attributable cancer risk in lung cancer screening with low-dose computed tomography." PloS one, Vol. 11 (No. 5), p. e0155722, (2016).
10- MS Linet et al., "Incidence of haematopoietic malignancies in US radiologic technologists." Occupational and environmental medicine, Vol. 62 (No. 12), pp. 861-67, (2005).
11- Elisabeth Cardis et al., "Risk of cancer after low doses of ionising radiation: retrospective cohort study in 15 countries." Bmj, Vol. 331 (No. 7508), p. 77, (2005).
12- Manon Britel, Michel Bourguignon, and Nicolas Foray, "The use of the term ‘radiosensitivity’through history of radiation: from clarity to confusion." International Journal of Radiation Biology, Vol. 94 (No. 5), pp. 503-12, (2018).
13- Saadat Ebrahimiyan, Alireza Montazerabadi, Hamed Masoumi, and Mohammad Keshtkar, "Assessment of some factors of cellular and humoral immunity in radiology workers." Radiation and Environmental Biophysics, Vol. 60 (No. 3), pp. 501-05, (2021).
14- Amirhossein Davoudian Talab, Zahra Farzanegan, and Farshid Mahmoudi, "Effects of occupational exposure on blood cells of radiographers working in Diagnostic Radiology Department of Khuzestan Province." Iranian Journal of Medical Physics, Vol. 15 (No. 2), pp. 66-70, (2018).
15- SS Puthran, K Sudha, GM Rao, and BV Shetty, "Oxidative stress and low dose ionizing radiation." Indian journal of physiology and pharmacology, Vol. 53 (No. 2), pp. 181-84, (2009).
16- L Schimmöller et al., "Evaluation of automated attenuation-based tube potential selection in combination with organ-specific dose reduction for contrast-enhanced chest CT examinations." Clinical radiology, Vol. 69 (No. 7), pp. 721-26, (2014).
17- Mohsen Shafiee, Elham Hoseinnezhad, Hassan Vafapour, Sajad Borzoueisileh, Mohammad Ghorbani, and Razieh Rashidfar, "Hematological findings in medical professionals involved at intraoperative fluoroscopy." Global Journal of Health Science, (2016).
18- Mahshid Sabagh and Ali Chaparian, "Evaluation of Blood Parameters of the Medical Radiation Workers." Iranian Journal of Medical Physics, Vol. 16 (No. 6), pp. 439-43, (2019).
19- Ali H Taqi, Kharman A Faraj, Sarah A Zaynal, Ahmed M Hameed, and Abd-Alkader A Mahmood, "Effects of occupational exposure of x-ray on hematological parameters of diagnostic technicians." Radiation Physics and Chemistry, Vol. 147pp. 45-52 ,(2018).
20- Mohammad Davoudi, Bijan Keikhaei, M Tahmasebi, and F Rahim, "Hematological profile change in radiation field workers." Apadana Journal of Clinical Research, Vol. 1 (No. 1), pp. 38-44, (2012).
21- A Hrycek, M Stieber, H Zielińska, and L Flakus, "Study of nitroblue tetrazolium reduction by granulocytes in workers handling x-ray equipment." Wiadomosci Lekarskie (Warsaw, Poland: 1960), Vol. 48 (No. 1-12), pp. 15-19,(1995).
22- Ahmet Godekmerdan, Mehmet Ozden, Ahmet Ayar, M Ferit Gursu, Ahmet Tevfik Ozan, and Selami Serhatlioglu, "Diminished cellular and humoral immunity in workers occupationally exposed to low levels of ionizing radiation." Archives of medical research, Vol. 35 (No. 4), pp. 28-324, (2004).
23- Saman Shahid, Nasir Mahmood, Muhammad Nawaz Chaudhry, Shaharyar Sheikh, and Nauman Ahmad, "Assessment of impacts of hematological parameters of chronic ionizing radiation exposed workers in hospitals." FUUAST Journal of Biology, Vol. 4 (No. 2), p. 135 ,(2014).
24- M Shafiee, R Rashidfar, S Borzoueisileh, M Ghorbani, H Vafapour, and S Rahimi, "The Effect of occupational exposure on blood parameters of radiology staffs in Yasuj", (2016).
25- Mazin R Mohammed et al., "Effects of radiation on the Hematological parameters in X-ray technicians: a case-control study." Journal of Pioneering Medical Sciences, Vol. 4 (No. 2), pp. 85-88, (2014).
26- NN Ratini, NLP Trisnawati, and GN Sutapa, "The quantity and leukocytes components as biological dosimeters on the radiation workers at Radiology Installation Sanglah General Hospital Denpasar, Bali-Indonesia." BALI MEDICAL JOURNAL, Vol. 7 (No. 3), pp. 564-68, (2018).
27- Surniyantoro Harry Nugroho Eko et al., "Assessment of Ionizing Radiation Effects on the Hematological Parameters of Radiation-Exposed Workers." Atom Indonesia, Vol. 45 (No. 2), pp. 123-29, (2019).
28- S Heydarheydari, A Haghparast, and MT Eivazi, "A novel biological dosimetry method for monitoring occupational radiation exposure in diagnostic and therapeutic wards: from radiation dosimetry to biological effects." Journal of Biomedical Physics & Engineering, Vol. 6 (No. 1), p. 21, (2016).
29- Sajedeh Zargan, Seyed Mohammad Seyedmehdi, HABIB Emami, MS Attarchi, and TARANEH Yazdanparast, "Comparison of blood cells in radiology workers and non-radiation workers staff of a governmental hospital in Tehran." Iran Occupational Health, Vol. 13 (No. 4), pp. 31-38, (2016).
2- Aytaç Altan and Seçkin Karasu, "Recognition of COVID-19 disease from X-ray images by hybrid model consisting of 2D curvelet transform, chaotic salp swarm algorithm and deep learning technique." Chaos, Solitons & Fractals, Vol. 140p. 110071, (2020).
3- Parnian Afshar et al., "COVID-CT-MD, COVID-19 computed tomography scan dataset applicable in machine learning and deep learning." Scientific Data, Vol. 8 (No. 1), pp. 1-8, (2021).
4- Ernesto Burgio, Prisco Piscitelli, and Lucia Migliore, "Ionizing radiation and human health: Reviewing models of exposure and mechanisms of cellular damage. An epigenetic perspective." International journal of environmental research and public health, Vol. 15 (No. 9), p. 1971 ,(2018).
5- Anju Shrivastava, Lalit Mohan Aggarwal, Surendra Pratap Mishra, Hari Dev Khanna, Uday Pratap Shahi, and Satyajit Pradhan, "Free radicals and antioxidants in normal versus cancerous cells—An overview." Indian Journal of Biochemistry and Biophysics (IJBB), Vol. 56 (No. 1), pp. 7-19, (2019).
6- Qin-Qi Wang et al., "Ionizing Radiation-Induced Brain Cell Aging and the Potential Underlying Molecular Mechanisms." Cells, Vol. 10 (No. 12), p. 3570, (2021).
7- Flávio Manoel Rodrigues da Silva-Júnior, Ronan Adler Tavella, Caroline Lopes Feijo Fernandes, Alexandra Silveira Mortola, Gianni Goulart Peraza, and Edariane Menestrino Garcia, "Genotoxic risk in health-care professionals occupationally exposed to low doses of ionizing radiation." Toxicology and Industrial Health, Vol. 36 (No. 5), pp. 356-70, (2020).
8- Ludwig E Feinendegen, Myron Pollycove, and Charles A Sondhaus, "Responses to low doses of ionizing radiation in biological systems." Nonlinearity in biology, toxicology, medicine, Vol. 2 (No. 3), p. 15401420490507431 ,(2004).
9- Natalia Saltybaeva, Katharina Martini, Thomas Frauenfelder, and Hatem Alkadhi, "Organ dose and attributable cancer risk in lung cancer screening with low-dose computed tomography." PloS one, Vol. 11 (No. 5), p. e0155722, (2016).
10- MS Linet et al., "Incidence of haematopoietic malignancies in US radiologic technologists." Occupational and environmental medicine, Vol. 62 (No. 12), pp. 861-67, (2005).
11- Elisabeth Cardis et al., "Risk of cancer after low doses of ionising radiation: retrospective cohort study in 15 countries." Bmj, Vol. 331 (No. 7508), p. 77, (2005).
12- Manon Britel, Michel Bourguignon, and Nicolas Foray, "The use of the term ‘radiosensitivity’through history of radiation: from clarity to confusion." International Journal of Radiation Biology, Vol. 94 (No. 5), pp. 503-12, (2018).
13- Saadat Ebrahimiyan, Alireza Montazerabadi, Hamed Masoumi, and Mohammad Keshtkar, "Assessment of some factors of cellular and humoral immunity in radiology workers." Radiation and Environmental Biophysics, Vol. 60 (No. 3), pp. 501-05, (2021).
14- Amirhossein Davoudian Talab, Zahra Farzanegan, and Farshid Mahmoudi, "Effects of occupational exposure on blood cells of radiographers working in Diagnostic Radiology Department of Khuzestan Province." Iranian Journal of Medical Physics, Vol. 15 (No. 2), pp. 66-70, (2018).
15- SS Puthran, K Sudha, GM Rao, and BV Shetty, "Oxidative stress and low dose ionizing radiation." Indian journal of physiology and pharmacology, Vol. 53 (No. 2), pp. 181-84, (2009).
16- L Schimmöller et al., "Evaluation of automated attenuation-based tube potential selection in combination with organ-specific dose reduction for contrast-enhanced chest CT examinations." Clinical radiology, Vol. 69 (No. 7), pp. 721-26, (2014).
17- Mohsen Shafiee, Elham Hoseinnezhad, Hassan Vafapour, Sajad Borzoueisileh, Mohammad Ghorbani, and Razieh Rashidfar, "Hematological findings in medical professionals involved at intraoperative fluoroscopy." Global Journal of Health Science, (2016).
18- Mahshid Sabagh and Ali Chaparian, "Evaluation of Blood Parameters of the Medical Radiation Workers." Iranian Journal of Medical Physics, Vol. 16 (No. 6), pp. 439-43, (2019).
19- Ali H Taqi, Kharman A Faraj, Sarah A Zaynal, Ahmed M Hameed, and Abd-Alkader A Mahmood, "Effects of occupational exposure of x-ray on hematological parameters of diagnostic technicians." Radiation Physics and Chemistry, Vol. 147pp. 45-52 ,(2018).
20- Mohammad Davoudi, Bijan Keikhaei, M Tahmasebi, and F Rahim, "Hematological profile change in radiation field workers." Apadana Journal of Clinical Research, Vol. 1 (No. 1), pp. 38-44, (2012).
21- A Hrycek, M Stieber, H Zielińska, and L Flakus, "Study of nitroblue tetrazolium reduction by granulocytes in workers handling x-ray equipment." Wiadomosci Lekarskie (Warsaw, Poland: 1960), Vol. 48 (No. 1-12), pp. 15-19,(1995).
22- Ahmet Godekmerdan, Mehmet Ozden, Ahmet Ayar, M Ferit Gursu, Ahmet Tevfik Ozan, and Selami Serhatlioglu, "Diminished cellular and humoral immunity in workers occupationally exposed to low levels of ionizing radiation." Archives of medical research, Vol. 35 (No. 4), pp. 28-324, (2004).
23- Saman Shahid, Nasir Mahmood, Muhammad Nawaz Chaudhry, Shaharyar Sheikh, and Nauman Ahmad, "Assessment of impacts of hematological parameters of chronic ionizing radiation exposed workers in hospitals." FUUAST Journal of Biology, Vol. 4 (No. 2), p. 135 ,(2014).
24- M Shafiee, R Rashidfar, S Borzoueisileh, M Ghorbani, H Vafapour, and S Rahimi, "The Effect of occupational exposure on blood parameters of radiology staffs in Yasuj", (2016).
25- Mazin R Mohammed et al., "Effects of radiation on the Hematological parameters in X-ray technicians: a case-control study." Journal of Pioneering Medical Sciences, Vol. 4 (No. 2), pp. 85-88, (2014).
26- NN Ratini, NLP Trisnawati, and GN Sutapa, "The quantity and leukocytes components as biological dosimeters on the radiation workers at Radiology Installation Sanglah General Hospital Denpasar, Bali-Indonesia." BALI MEDICAL JOURNAL, Vol. 7 (No. 3), pp. 564-68, (2018).
27- Surniyantoro Harry Nugroho Eko et al., "Assessment of Ionizing Radiation Effects on the Hematological Parameters of Radiation-Exposed Workers." Atom Indonesia, Vol. 45 (No. 2), pp. 123-29, (2019).
28- S Heydarheydari, A Haghparast, and MT Eivazi, "A novel biological dosimetry method for monitoring occupational radiation exposure in diagnostic and therapeutic wards: from radiation dosimetry to biological effects." Journal of Biomedical Physics & Engineering, Vol. 6 (No. 1), p. 21, (2016).
29- Sajedeh Zargan, Seyed Mohammad Seyedmehdi, HABIB Emami, MS Attarchi, and TARANEH Yazdanparast, "Comparison of blood cells in radiology workers and non-radiation workers staff of a governmental hospital in Tehran." Iran Occupational Health, Vol. 13 (No. 4), pp. 31-38, (2016).
| Files | ||
| Issue | Vol 10 No 1 (2023) | |
| Section | Short Report(s) | |
| DOI | https://doi.org/10.18502/fbt.v10i1.11517 | |
| Keywords | ||
| Blood Parameters Low Dose X-Ray Radiation Effect | ||
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How to Cite
1.
Keshtkar M, Khaghani N, Ziaee M, Pandesh S. Comparison of Hematological Parameters between Diagnostic Radiation Workers and Non-Radiation Workers. Frontiers Biomed Technol. 2022;10(1):96-101.
