Lifetime Attributable Breast Cancer Risk Related to Lung CT Scan in Women with Covid19
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Abstract
Purpose: Evaluating organ radiation doses and also lifetime risk (LAR) of breast cancer from lung CT scans of 735 female patients from the age of 20-50 with Covid19 surveyed by four Corona center hospitals in Tehran, Iran. Patients’ data and exposure information were extracted from dose report pages in picture archiving and communication systems.
Materials and methods: Patients were divided into six age groups 20-25; 25-30; 30-35; 35–40; 40-45 and 45–50 years. Breast, thyroid, lung and heart doses were calculated by NCICT, and LAR of breast cancer incidence has been evaluated by BEIR VII report.
Results: The average dose of breast, thyroid, lung and heart were 3.97, 4.75, 4.10 and 3.37 mGy and also the average of the effective dose was 2.56 mSv. Also, the average LAR of breast cancer in female patients was 7.45 per 100,000 exposures and it decreased with age.
Conclusion: Although CT scan is a useful instrument in the diagnosis and treatment of Corona disease, but it should be recommended with caution due to the increased risk of breast cancer, especially in younger women.
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27- Atefeh Tahmasebzadeh, Asghar Maziyar, Reza Reiazi, Mojtaba Soltani Kermanshahi, Seyyed Hossein Mousavie Anijdan, and Reza Paydar, "Pediatric effective dose assessment for routine computed tomography examinations in Tehran, Iran." Journal of Medical Signals and Sensors, Vol. 12 (No. 3), pp. 227-32, (2022).
28- Dan Wang et al., "Image quality and dose performance of 80 kV low dose scan protocol in high-pitch spiral coronary CT angiography: feasibility study." The International Journal of Cardiovascular Imaging, Vol. 28 (No. 2), pp. 415-23, (2012).
29- Bernhard Bischoff et al., "Impact of a reduced tube voltage on CT angiography and radiation dose: results of the PROTECTION I study." JACC: Cardiovascular Imaging, Vol. 2 (No. 8), pp. 940-46, (2009).
30- Gilbert L Raff et al., "Radiation dose from cardiac computed tomography before and after implementation of radiation dose–reduction techniques." Jama, Vol. 301 (No. 22), pp. 2340-48, (2009).
31- Daisuke Yamazaki et al., "Usefulness of size-specific dose estimates in pediatric computed tomography: revalidation of large-scale pediatric CT dose survey data in Japan." Radiation Protection Dosimetry, Vol. 179 (No. 3), pp. 254-62, (2018).
32- MT Russell, JR Fink, F Rebeles, K Kanal, M Ramos, and Y Anzai, "Balancing radiation dose and image quality: clinical applications of neck volume CT." American journal of neuroradiology, Vol. 29 (No. 4), pp. 727-31, (2008).
33- II Suliman, HM Khamis, TH Ombada, K Alzimami, M Alkhorayef, and A Sulieman, "Radiation exposure during paediatric CT in Sudan: CT dose, organ and effective doses." Radiation Protection Dosimetry, Vol. 167 (No. 4), pp. 513-18, (2015).
34- Gilbert L Raff, "Radiation dose from coronary CT angiography: five years of progress." Journal of cardiovascular computed tomography, Vol. 4 (No. 6), pp. 365-74, (2010).
2- World Health Organization, "Naming the coronavirus disease (COVID-19) and the virus that causes it." Brazilian Journal Of Implantology And Health Sciences, Vol. 2 (No. 3), (2020).
3- Ethiopia Coronavirus, "13,968 Cases and 223 Deaths: https://www. worldometers. info/coronavirus/country/ethiopia." Accessed on, Vol. 27(2020).
4- Christian A Devaux, Jean-Christophe Lagier, and Didier Raoult, "New insights into the physiopathology of COVID-19: SARS-CoV-2-associated gastrointestinal illness." Frontiers in medicine, Vol. 8p. 640073, (2021).
5- Vruddhi Shah, Rinkal Keniya, Akanksha Shridharani, Manav Punjabi, Jainam Shah, and Ninad Mehendale, "Diagnosis of COVID-19 using CT scan images and deep learning techniques." Emergency radiology, Vol. 28 (No. 3), pp. 497-505, (2021).
6- John D Mathews et al., "Cancer risk in 680 000 people exposed to computed tomography scans in childhood or adolescence: data linkage study of 11 million Australians." Bmj, Vol. 346(2013).
7- WY Huang et al., "Paediatric head CT scan and subsequent risk of malignancy and benign brain tumour: a nation-wide population-based cohort study." British journal of cancer, Vol. 110 (No. 9), pp. 2354-60, (2014).
8- Amy Berrington de Gonzalez, Elisa Pasqual, and Lene Veiga, "Epidemiological studies of CT scans and cancer risk: the state of the science." The British Journal of Radiology, Vol. 94p. 20210471, (2021).
9- Justin E Costello, Nathan D Cecava, Jonathan E Tucker, and Jennifer L Bau, "CT radiation dose: current controversies and dose reduction strategies." American journal of roentgenology, Vol. 201 (No. 6), pp. 1283-90, (2013).
10- Adnan Lahham, Hussein ALMasri, and Saleh Kameel, "Estimation of female radiation doses and breast cancer risk from chest CT examinations." Radiation Protection Dosimetry, Vol. 179 (No. 4), pp. 303-09, (2018).
11- A Carmichael, AS Sami, and JM Dixon, "Breast cancer risk among the survivors of atomic bomb and patients exposed to therapeutic ionising radiation." European Journal of Surgical Oncology (EJSO), Vol. 29 (No. 5), pp. 475-79, (2003).
12- National Research Council, "Health risks from exposure to low levels of ionizing radiation: BEIR VII phase 2." (2006).
13- Mehmet Halit Yilmaz et al., "Female breast radiation exposure during thorax multidetector computed tomography and the effectiveness of bismuth breast shield to reduce breast radiation dose." Journal of computer assisted tomography, Vol. 31 (No. 1), pp. 138-42, (2007).
14- Michael F McNitt-Gray, "AAPM/RSNA physics tutorial for residents: topics in CT: radiation dose in CT." Radiographics, Vol. 22 (No. 6), pp. 1541-53, (2002).
15- Johanna M Meulepas et al., "Response to Wollschläger, Blettner, and Pokora." JNCI: Journal of the National Cancer Institute, Vol. 111 (No. 9), pp. 1002-03, (2019).
16- United Nations Scientific Committee, "the Effects of Atomic Radiation, Sources and effects of ionizing radiation Annex D. Health effects due to radiation from the Chernobyl accident." http://www. unscear. org/unscear/en/publications. html, (2008).
17- Magda Bosch de Basea et al., "Subtle excess in lifetime cancer risk related to CT scanning in Spanish young people." Environment international, Vol. 120pp. 1-10, (2018).
18- Amy Berrington De González et al., "Projected cancer risks from computed tomographic scans performed in the United States in 2007." Archives of internal medicine, Vol. 169 (No. 22), pp. 2071-77, (2009).
19- Anthony B Miller et al., "Mortality from breast cancer after irradiation during fluoroscopic examinations in patients being treated for tuberculosis." New England Journal of Medicine, Vol. 321 (No. 19), pp. 1285-89, (1989).
20- Atefeh Tahmasebzadeh, Reza Paydar, Mojtaba Soltani-Kermanshahi, Asghar Maziar, and Reza Reiazi, "Lifetime attributable cancer risk related to prevalent CT scan procedures in pediatric medical imaging centers." International Journal of Radiation Biology, Vol. 97 (No. 9), pp. 1282-88, (2021).
21- Seyed Mohammad Bagher Hosseini Nasab, Mohammad Reza Deevband, Ali Shabestani-Monfared, Seyed Ali Hoseini Amoli, and Seyed Hasan Fatehi Feyzabad, "Organ equivalent dose and lifetime attributable risk of cancer incidence and mortality associated with cardiac CT angiography." Radiation Protection Dosimetry, Vol. 189 (No. 2), pp. 213-23, (2020).
22- Erin Angel et al., "Dose to radiosensitive organs during routine chest CT: effects of tube current modulation." AJR. American journal of roentgenology, Vol. 193 (No. 5), p. 1340, (2009).
23- Rebecca Smith-Bindman et al., "Radiation dose associated with common computed tomography examinations and the associated lifetime attributable risk of cancer." Archives of internal medicine, Vol. 169 (No. 22), pp. 2078-86, (2009).
24- Desmond E Thompson et al., "Cancer incidence in atomic bomb survivors. Part II: Solid tumors, 1958-1987." Radiation research, Vol. 137 (No. 2s), pp. S17-S67, (1994).
25- Kashish Goel and Kim Allan Williams, "Reduction of Radiation Doses in Cardiac Imaging, Part II: New Advances and Techniques in Nuclear Perfusion Imaging and Cardiac CT." Current Cardiovascular Imaging Reports, Vol. 4 (No. 3), pp. 244-50, (2011).
26- Atefeh Tahmasebzadeh, Reza Paydar, Mojtaba Soltani kermanshahi, Asghar Maziar, Mehdi Rezaei, and Reza Reiazi, "Pediatric regional Drl assessment in common Ct examinations for medical exposure optimization in Tehran, Iran." Radiation Protection Dosimetry, Vol. 192 (No. 3), pp. 341-49, (2020).
27- Atefeh Tahmasebzadeh, Asghar Maziyar, Reza Reiazi, Mojtaba Soltani Kermanshahi, Seyyed Hossein Mousavie Anijdan, and Reza Paydar, "Pediatric effective dose assessment for routine computed tomography examinations in Tehran, Iran." Journal of Medical Signals and Sensors, Vol. 12 (No. 3), pp. 227-32, (2022).
28- Dan Wang et al., "Image quality and dose performance of 80 kV low dose scan protocol in high-pitch spiral coronary CT angiography: feasibility study." The International Journal of Cardiovascular Imaging, Vol. 28 (No. 2), pp. 415-23, (2012).
29- Bernhard Bischoff et al., "Impact of a reduced tube voltage on CT angiography and radiation dose: results of the PROTECTION I study." JACC: Cardiovascular Imaging, Vol. 2 (No. 8), pp. 940-46, (2009).
30- Gilbert L Raff et al., "Radiation dose from cardiac computed tomography before and after implementation of radiation dose–reduction techniques." Jama, Vol. 301 (No. 22), pp. 2340-48, (2009).
31- Daisuke Yamazaki et al., "Usefulness of size-specific dose estimates in pediatric computed tomography: revalidation of large-scale pediatric CT dose survey data in Japan." Radiation Protection Dosimetry, Vol. 179 (No. 3), pp. 254-62, (2018).
32- MT Russell, JR Fink, F Rebeles, K Kanal, M Ramos, and Y Anzai, "Balancing radiation dose and image quality: clinical applications of neck volume CT." American journal of neuroradiology, Vol. 29 (No. 4), pp. 727-31, (2008).
33- II Suliman, HM Khamis, TH Ombada, K Alzimami, M Alkhorayef, and A Sulieman, "Radiation exposure during paediatric CT in Sudan: CT dose, organ and effective doses." Radiation Protection Dosimetry, Vol. 167 (No. 4), pp. 513-18, (2015).
34- Gilbert L Raff, "Radiation dose from coronary CT angiography: five years of progress." Journal of cardiovascular computed tomography, Vol. 4 (No. 6), pp. 365-74, (2010).
| Files | ||
| Issue | Vol 11 No 1 (2024) | |
| Section | Original Article(s) | |
| DOI | https://doi.org/10.18502/fbt.v11i1.14513 | |
| Keywords | ||
| Computed Tomography Scan Breast Cancer Covid19 Lung | ||
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How to Cite
1.
Tahmasebzadeh A, Paydar R, Kaeidi H. Lifetime Attributable Breast Cancer Risk Related to Lung CT Scan in Women with Covid19. Frontiers Biomed Technol. 2023;11(1):69-74.
