Calculation of Dose Perturbation in Radiotherapy of Head and Neck Tumors Due to the Presence of Dental Implants: A Monte Carlo Study
-
Morteza Hashemizadeh
,
Nasim Shams
,
Mansour Zabihzadeh
,
Masoud Jamali
,
Zeinab Sedaghat
,
Omid Azadbakht
Abstract
Purpose: The presence of a dental implant across the irradiation beam has the potential to perturb the dose distribution. In this study, the effect of different commercial dental implants on dose distribution was investigated in electron beam therapy.
Materials and Methods: The Varian 2100 C/D linear accelerator (Linac) head was modeled precisely with proper components for electron mode (6 and 9 MeV) by MCNPX 2.6.1 and was benchmarked according to the International Atomic Energy Agency (IAEA) protocol, TRS -398. Dose distribution was calculated for Six different implant materials, including Titanium, Titanium alloy, Zirconia (Y-TZP), Zirconium oxide, Alumina, and PolyetherEtherKetone (PEEK), and for Four different scenarios.
Results: The highest and lowest increasing doses occurred for Y-TZP (114.44% and 108.69% for 6 and 9 MeV, respectively) and PEEK (104.85% and 98.84% for 6 and 9 MeV, respectively) directly in front of the implant, respectively. By removing an implant from the jaw, an increasing dose was not seen, but an increasing dose occurred behind its depths in the bone region (31.81 %).
Conclusion: The amount of dose perturbation due to the dental implant's presence depends on the beam energy, mass density, and atomic numbers of implants. Maximum and minimum increased doses were estimated for Y-TZP and PEEK implants, respectively. Considering the correction factors due to the presence of high density and atomic number dental implants are essential to estimate the accurate dose delivery in radiotherapy with electron beams.
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32- Thomas Binger, H. Seifert, G. Blass, K. H. Bormann, and M. Rücker, "Dose inhomogeneities on surfaces of different dental implants during irradiation with high-energy photons." Dentomaxillofacial Radiology, Vol. 37 (No. 3), pp. 149-53, (2008).
2- M. Beyzadeoglu, B. Dirican, K. Oysul, J. Ozen, and O. Ucok, "Evaluation of scatter dose of dental titanium implants exposed to photon beams of different energies and irradiation angles in head and neck radiotherapy." Dentomaxillofacial Radiology, Vol. 35 (No. 1), pp. 14-17, 2006/1// (2006).
3- Reham B. Osman and Michael V. Swain, "A Critical Review of Dental Implant Materials with an Emphasis on Titanium versus Zirconia." Materials, Vol. 8pp. 932-58, (2015).
4- Reinhard E. Friedrich, Manuel Todorovic, Max Heiland, Hanna A. Scheuer, and Andreas Krüll, "Scattering effects of irradiation on surroundings calculated for a small dental implant." Anticancer Research, Vol. 32 (No. 5), pp. 2043-46, (2012).
5- Zeynep Özkurt and Ender Kazazoğlu, "Zirconia Dental Implants: A Literature Review." Journal of Oral Implantology, Vol. 37 (No. 3), pp. 367-76, 2011/6// (2011).
6- Andreas Dominik Schwitalla, Tobias Spintig, Ilona Kallage, and Wolf Dieter Müller, "Flexural behavior of PEEK materials for dental application." Dental Materials, Vol. 31 (No. 11), pp. 1377-84, 2015/11// (2015).
7- Oya Akyol, Turan Olgar, Turkay Toklu, Hakan Eren, and Bahar Dirican, "Dose distrubution evaluation of different dental implants on a real human dry-skull model for head and neck cancer radiotherapy." Radiation Physics and Chemistry, Vol. 189pp. 109751-51, 2021/12// (2021).
8- Bernd Reitemeier et al., "Evaluation of a device for attenuation of electron release from dental restorations in a therapeutic radiation field." The Journal of Prosthetic Dentistry, Vol. 87 (No. 3), pp. 323-27, 2002/3// (2002).
9- David W. H. Chin et al., "Effect of dental restorations and prostheses on radiotherapy dose distribution: A monte carlo study." Journal of Applied Clinical Medical Physics, Vol. 10 (No. 1), pp. 80-89, (2009).
10- Julide Ozen, Bahar Dirican, Kaan Oysul, Murat Beyzadeoglu, Ozlem Ucok, and Bedri Beydemir, "Dosimetric evaluation of the effect of dental implants in head and neck radiotherapy." Oral Surgery, Oral Medicine, Oral Pathology, Oral Radiology and Endodontology, Vol. 99 (No. 6), pp. 743-47, (2005).
11- J. Beumer, R. Harrison, B. Sanders, and M. Kurrasch, "Osteoradionecrosis: predisposing factors and outcomes of therapy." Head & neck surgery, Vol. 6 (No. 4), pp. 819-27, (1984).
12- M. M. Curi and L. L. Dib, "Osteoradionecrosis of the jaws: a retrospective study of the background factors and treatment in 104 cases." Journal of oral and maxillofacial surgery: official journal of the American Association of Oral and Maxillofacial Surgeons, Vol. 55 (No. 6), pp. 540-46, 1997/6// (1997).
13- Norah Duv Tapley and G. H. Fletcher, "The Electron Beam in the Treatment of Oral Cavity and Oropharynx Cancer and in ‘Boost’ Therapy1." Vol. 2, Electron Beam Therapy: 2nd Annual San Francisco Cancer Symposium, San Francisco, Cal., October 1966: Proceedings: S.Karger AG, (1968), p. 0. [Online]. Available: https://doi.org/10.1159/000426729.
14- Ashutosh Mukherji, "Planning Electron Therapy and Evaluation of Plans." in Basics of Planning and Management of Patients during Radiation Therapy: A Guide for Students and Practitioners, Ashutosh Mukherji, Ed. Singapore: Springer Singapore, (2018), pp. 209-19.
15- W. Dobrowsky, O. Schlappack, K. H. Kärcher, R. Pavelka, and G. Kment, "Electron beam therapy in treatment of parotid neoplasm." (in eng), Radiother Oncol, Vol. 6 (No. 4), pp. 293-9, Aug (1986).
16- C. M. Menard, J. Bews, R. I. Skoracki, and A. D. Chowdhury, "High-energy electron and photon therapy to the parotid bed: radiation dose perturbations with a titanium mandibular implant." Australas Radiol, Vol. 43 (No. 4), pp. 495-9, Nov (1999).
17- D. W. O. Rogers and A. F. Bielajew, "Monte Carlo techniques of electron and photon transport for radiation dosimetry." The dosimetry of ionizing radiation, Vol. 3pp. 427-539, (1990).
18- Philip von Voigts-Rhetz, Damian Czarnecki, and Klemens Zink, "Effective point of measurement for parallel plate and cylindrical ion chambers in megavoltage electron beams." Zeitschrift für Medizinische Physik, Vol. 24 (No. 3), pp. 216-23, 2014/09/01/ (2014).
19- Gregg McKinney, MCNPX User's Manual, Version 2.6.0. (2008).
20- J Kenneth Shultis and Richard E Faw, "An MCNP primer." (2011).
21- Daryoush Sheikh-Bagheri and D. W. O. Rogers, "Sensitivity of megavoltage photon beam Monte Carlo simulations to electron beam and other parameters." medical physics, Vol. 29 (No. 3), pp. 379-90, 2002/03/01 (2002).
22- Tsuyoshi Kato, Shinichiro Omachi, and Hirotomo Aso, "Asymmetric gaussian and its application to pattern recognition." Springer, pp. 405-13.
23- Faiz M. Khan and John P. Gibbons, Khan's the physics of radiation therapy. 5th editio ed. Philadelphia: Lippincott Williams & Wilkins, (2014).
24- Kenneth R. Hogstrom and Peter R. Almond, "Review of electron beam therapy physics." Physics in Medicine and Biology, Vol. 51 (No. 13), (2006).
25- F. Seif, T. Seif, M. Athari, M. R. Bayatiyani, and S. Bagheri, "Investigating the effect of dental implants on radiotherapy dose distribution using mont carlo approach." Journal of Babol University of Medical Sciences, Vol. 20 (No. 8), pp. 56-61, (2018).
26- Oya Akyol, Bahar Dirican, Turkay Toklu, Hakan Eren, and Turan Olgar, "Investigating the effect of dental implant materials with different densities on radiotherapy dose distribution using Monte-Carlo simulation and pencil beam convolution algorithm." Dentomaxillofacial Radiology, Vol. 48 (No. 4), pp. 20180267-67, 2019/5// (2019).
27- G. Khaleghi et al., "Investigating dose homogeneity in radiotherapy of oral cancers in the presence of a dental implant system: an in vitro phantom study." Int J Implant Dent, Vol. 7 (No. 1), p. 90, Sep 6 (2021).
28- P. Saadatmand, A. Amouheidari, A. Shanei, and I. Abedi, "Dose perturbation due to dental amalgam in the head and neck radiotherapy: A phantom study." Med Dosim, Vol. 45 (No. 2), pp. 128-33, Summer (2020).
29- M. Azizi, A. A. Mowlavi, M. Ghorbani, C. Knuap, and M. Behmadi, "A Monte Carlo study on dose perturbation due to dental restorations in a 15 MV photon beam." J Cancer Res Ther, Vol. 15 (No. 3), pp. 491-97, Jul-Sep (2019).
30- Reinhard E. Friedrich, Todrovic And Manuel, and Krull Andreas, "Simulation of scattering effects of irradiation on surroundings using the example of titanium dental implants: A Monte Carlo approach." Anticancer Research, Vol. 30 (No. 5), pp. 1727-30, (2010).
31- Serap Çatli, "High-density dental implants and radiotherapy planning: Evaluation of effects on dose distribution using pencil beam convolution algorithm and Monte Carlo method." Journal of Applied Clinical Medical Physics, Vol. 16 (No. 5), pp. 46-52, (2015).
32- Thomas Binger, H. Seifert, G. Blass, K. H. Bormann, and M. Rücker, "Dose inhomogeneities on surfaces of different dental implants during irradiation with high-energy photons." Dentomaxillofacial Radiology, Vol. 37 (No. 3), pp. 149-53, (2008).
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| Issue | Vol 11 No 4 (2024) | |
| Section | Original Article(s) | |
| DOI | https://doi.org/10.18502/fbt.v11i4.16514 | |
| Keywords | ||
| Dental Implant Dose Distribution Electron Therapy Monte Carlo Calculation Radiotherapy Head and Neck Tumors | ||
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How to Cite
1.
Hashemizadeh M, Shams N, Zabihzadeh M, Jamali M, Sedaghat Z, Azadbakht O. Calculation of Dose Perturbation in Radiotherapy of Head and Neck Tumors Due to the Presence of Dental Implants: A Monte Carlo Study. Frontiers Biomed Technol. 2024;11(4):651-661.
