Injectable Nano-Chitosan /CaCO3 (NCsC) Composite As Noval Pulpotomy Paste in Partially Pulpotomized Rabbit Incisors
,
Abstract
Purpose: apply of tissue-engineering principles to generate simple and effective dental pulp capping material represent a promising therapeutic option for treating immature and mature tooth with compromised pulp vitality. The aim of the study was to evaluate the pathophysiological response of the pulp to (nano-chitosan/CaCO3) scaffold as potential novel capping material on traumatically exposed pulp of rabbit incisors.
Material and methods:24 lower central incisors of New Zealand rabbits were used, subdivided into two group of 12 teeth according to sacrificing time (1 and 4 week), in each group, six teeth were used as control group, the pulp is traumatically exposed and partially amputated left free of capping material, and the other six teeth used as experimental group ,were the amputated pulp capped with (nano-chitosan/CaCO3) ,the cavity of both groups sealed with resin modified glass ionomere cement .animal were sacrificed and teeth were collected for histological examination
Results: At 1 week, both groups showed non-significant difference in inflammatory extent, high significant difference in calcific bridge formation (P=0.002) .and dentin morphology (P=0.002) . at 4 week period there is non-significant difference in inflammatory response ,high significant difference in dentine bridge formation (P=0.002) but non -significant difference in the dentin morphology (P=0.06) group, (nano-chitosan/CaCO3) showed faster dentin bridge formation in both period compared to control group
Conclusions: (nano-chitosan/CaCO3) composite is promising novel pulpotomy material
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| Files | ||
| Issue | Vol 13 No 2 (2026) | |
| Section | Original Article(s) | |
| DOI | https://doi.org/10.18502/fbt.v13i2.21935 | |
| Keywords | ||
| Tissue Engineering Scaffold Nano-Chitosan CaCO3 Composite Rabbit Incisors | ||
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This work is licensed under a Creative Commons Attribution-NonCommercial 4.0 International License. |
How to Cite
1.
abdulhussain ali A, Kadhim EF. Injectable Nano-Chitosan /CaCO3 (NCsC) Composite As Noval Pulpotomy Paste in Partially Pulpotomized Rabbit Incisors. Frontiers Biomed Technol. 2026;13(2):365-375.
